On September 21, 2022, First Lady Dr. Jill Biden and Queen Letizia of Spain visited the Columbia University Irving Medical Center to learn first-hand about the work that the Cancer Moonshot is doing to advance treatments, cures, patient care, and prevention. Their visit, following their June 2022 joint visit to the Spanish Association Against Cancer in Madrid, demonstrates their commitment to end cancer as we know it, and to highlight the importance of research and international cooperation in the fight against this disease.